发明名称 Alpha amino-acids
摘要 <p>(A) alpha-Amino-acids of general formula:- (I) M = alkyl, H or alkali metal R3 and R4 = H and/or alkyl or R3 and R4, when in o-position, together form a methylene group. n = 0, 1 or 2 (B) Acid addition salts of (I) with organic and inorganic acids. (C) Intermediates in the synthesis of (I) (see "Preparation"). (I) are active as decarboxylase-inhibitors in man and animals. Also very valuable anti-hypertensive agents which may be used in cases of virulent hypertension. May also be used as intermediates in the production of norepinephrinic cpds. which are used as pressor-agents.</p>
申请公布号 CH521947(A) 申请公布日期 1972.04.30
申请号 CH19650003090 申请日期 1965.03.05
申请人 MERCK & CO., INC. 发明人 SLETZINGER,MEYER;ARMOND FIRESTONE,RAYMOND;FLOYD REINHOLD,DONALD
分类号 A61K31/135;(IPC1-7):C07C101/30 主分类号 A61K31/135
代理机构 代理人
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