发明名称 |
System and method for real-time diagnosis, treatment, and therapeutic drug monitoring |
摘要 |
Systems and methods for diagnosing and/or treating diseases as well as monitoring disease treatment. For diagnosis, the present invention uses nanoparticle-based assemblies, which comprise a nanoparticle; a surrogate marker; and a means for detecting a specific chemical entity. In certain embodiments, nanoparticle-based assemblies include a payload for simultaneous diagnosis and treatment of disease. In further embodiments, a therapeutic drug and therapeutic drug marker are administered to a patient to monitor disease treatment. Bodily fluid samples are analyzed using sensor technology to detect the presence of surrogate and/or therapeutic drug markers to provide an efficient and accurate means for diagnosing a disease and/or monitoring disease treatment. |
申请公布号 |
EP1990639(A1) |
申请公布日期 |
2008.11.12 |
申请号 |
EP20080161973 |
申请日期 |
2005.02.28 |
申请人 |
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
MELKER, RICHARD J.;SACKELLARES, JAMES CHRIS;GOLD, MARK S.;DENNIS, DONN MICHAEL;MARTIN, CHARLES R.;STEWART, JON D. |
分类号 |
G01N33/543;A61B5/08;A61B5/083;A61B5/11;A61K9/51;A61M5/142;A61M5/172;A61M16/01;A61M16/10;G01N33/497;G01N33/50;G01N33/53 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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