| 发明名称 |
Plks as Modifiers of the Beta Catenin Pathway and Methods of Use |
| 摘要 |
Human PLK genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of PLK are provided.
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| 申请公布号 |
US2008274122(A1) |
申请公布日期 |
2008.11.06 |
| 申请号 |
US20040580131 |
申请日期 |
2004.11.23 |
| 申请人 |
EXELIXIS, INC. |
发明人 |
FRANCIS-LANG HELEN;WINTER CHRISTOPHER G.;VENTURA RICHARD BENN ABEGANIA;BJERKE LYNN MARGARET;HEUER TIMOTHY S. |
| 分类号 |
A61K39/395;A61K;A61K31/70;A61P31/00;C12N;C12Q1/02;C12Q1/48;C12Q1/68;G01N33/53;G01N33/573;G01N33/574 |
主分类号 |
A61K39/395 |
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