| 摘要 |
A method for preparing composite microspheres of a high-molecular material and a core substance includes the steps of: dissolving a high-molecular material and dispersing a core substance in a high pressure fluid containing a supercritical fluid and an entrainer, under a shear stress of 1 Pa or more; and spraying the resultant high pressure fluid containing the high-molecular material and the core substance into a poor solvent to cause rapid expansion. According to the method composite microspheres having a uniform size of several micrometers or less, and more preferably nanometer order (a size of 1 mum or less) can be obtained.
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