发明名称 |
AZA-PEPTIDE MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS |
摘要 |
<p>The present invention relates to compounds of Formula (I), or a pharmaceutically acceptable salt, ester, or prodrug, which inhibit serine protease activity, particularly the activity of hepatitis C virus (HCV) NS3-NS4A protease. Consequently, the compounds of the present invention interfere with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.</p> |
申请公布号 |
WO2008134395(A1) |
申请公布日期 |
2008.11.06 |
申请号 |
WO2008US61375 |
申请日期 |
2008.04.24 |
申请人 |
ENANTA PHARMACEUTICALS, INC.;OR, YAT SUN;NIU, DEQIANG;WANG, ZHE |
发明人 |
OR, YAT SUN;NIU, DEQIANG;WANG, ZHE |
分类号 |
A01N43/04;A61K31/70 |
主分类号 |
A01N43/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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