发明名称 GLYCOSYLATION OF PEPTIDES VIA O-LINKED GLYCOSYLATION SEQUENCES
摘要 The present invention provides sequon polypeptides with an amino acid sequence including one or more exogenous O-linked glycosylation sequence of the invention. In addition, the present invention provides methods of making polypeptide conjugates as well as methods of using such conjugates and their pharmaceutical compositions. The invention further provides libraries of sequon polypeptides, wherein each member of such library includes at least one exogenous O-linked glycosylation sequence of the invention. Also provided are methods of making and using such libraries.
申请公布号 US2008274958(A1) 申请公布日期 2008.11.06
申请号 US20070781900 申请日期 2007.07.23
申请人 NEOSE TECHNOLOGIES, INC. 发明人 DEFREES SHAWN
分类号 A61K38/00;C07H21/04;C07K14/00;C07K16/00;C12N5/00;C12N9/00;C12N15/00;C12N15/87;C12P21/06;C40B20/00;C40B20/08;C40B40/10;C40B50/06 主分类号 A61K38/00
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