发明名称 |
Rabies Virus Vector Systems and Compositions and Methods Thereof |
摘要 |
Rabies Virus compositions and methods are provided. The full-length sequence of Rabies Virus strain Evelyn-Rokitnicki-Abelseth (ERA) is disclosed. A reverse genetics system for producing recombinant ERA virus and derivatives thereof is provided, along with compositions including ERA and/or ERA derivative strain viruses, nucleic acids and/or proteins. In some instances, the compositions are immunogenic compositions useful for the pre- or post-exposure treatment of Rabies Virus.
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申请公布号 |
US2008274130(A1) |
申请公布日期 |
2008.11.06 |
申请号 |
US20060090083 |
申请日期 |
2006.10.13 |
申请人 |
THE GOVT. OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT.OF HEALTH AND HUMAN SERVICES |
发明人 |
RUPPRECHT CHARLES E.;WU XIANFU |
分类号 |
A61K39/12;A61K38/16;C07H21/04;C07K14/005;C12N15/00;C12N15/74;C12Q1/70 |
主分类号 |
A61K39/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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