| 摘要 |
The present invention discloses a selective culture medium for detecting MRSA and selective drug or multidrug resistant microorganisms where the expression of said (multi)drug resistance is by virtue of the production by said microorganisms of &bgr;-lactamase enzymes. The medium comprises: (i) a broad spectrum antibiotic capable of selectively inhibiting growth/replication of (a) organisms that do not produce &bgr;-lactamase enzymes, (b) organisms that while producing &bgr;-lactamase do not exhibit an ESBL or AmpC phenotype and (c) Methicillin-susceptible S. aureus, and (ii) a compound capable of inducing production of &bgr;-lactamases in an organism, and which compound is included at a concentration that is subinhibitory for growth of said microorganism. Also provided are a method and kit for selectively isolating any MRSA and/or ESBL, or AmpC &bgr;-lactamase producing microorganisms present in a sample using the selective culture medium. |
