发明名称 |
Cysteine string protein and its role in neurodegenerative diseases |
摘要 |
The present invention relates to in vitro and in vivo assays for the identification of agents that are useful in the treatment of neurodegenerative diseases that are associated with defects in protein folding. The present further relates to in vitro and in vivo assays for the identification of agents that contribute to the neurodegenerative processes which occur in these diseases. The present invention also relates to in vitro and in vivo models of neurodegenerative diseases. These assays and models will be useful in further understanding the pathogenesis of various neurodegenerative diseases in which defects in protein folding have been implicated, in identifying additional endogenous or environmental factors that contribute to the etiologies of these diseases, and in developing effective therapies for the prevention and/or treatment of these diseases.
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申请公布号 |
US7445904(B2) |
申请公布日期 |
2008.11.04 |
申请号 |
US20020255989 |
申请日期 |
2002.09.26 |
申请人 |
SUEDHOF THOMAS C;STAHL BERND;TOBABEN SOENKE |
发明人 |
SUEDHOF THOMAS C;STAHL BERND;TOBABEN SOENKE |
分类号 |
G01N33/567;A61K49/00;C12N15/85;G01N33/53 |
主分类号 |
G01N33/567 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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