摘要 |
Multiply-charged ions are generated from singly-charged ions of analyte substances. The singly-charged ions, which are supplied by many types of ion sources, are accelerated, together with donor ions of substances which have only a very low proton affinity, into a reaction cell. In the reaction cell, protons are transferred from the donor ions to the analyte ions to protonate the analyte ions and increase the ion charge. The multiply-charged analyte ions are subsequently fragmented by a variety of techniques and mass analyzed.
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