Bioartificial implant and its use and method of reducing the risk for formation of connective tissue after implantation

摘要

Provided is a bioartificial implant comprising a semipermeable barrier designed, from one side to allow diffusion or prevent diffusion of predetermined substances / materials / molecules / cells / cell lines to the other opposite side of the barrier; and from said other opposite side to allow diffusion or prevent diffusion of predetermined substances which are the same as or different from the first mentioned substances / materials / molecules / cells / cell lines, wherein said semipermeable barrier has a surface coating of a bioactive metal, said surface coating being permeable to allow or prevent said diffusions. Further provided are implants made of titanium, zirconium, tantalum or an alloy thereof, an insulin pump comprising such an implant and a method of reducing the risk of formation or growth of connective tissue adjacent to the implant.