发明名称 METHOD FOR DIAGNOSIS OF NON-SMALL CELL CARCINOMA OF LUNG AND A KIT THEREFOR
摘要 The invention relates to medicine, in particular to oncology and molecular biology and discloses the use of transcriptional level of a TIMP3 gene in the form of a diagnosis marker for a non-small cell carcinoma of lung. The decreased transcriptional level in a human tissue which is invaded by cancer for a long time in comparison with the level thereof in a sound tissue is used in the form of a diagnosis character of a non-small cell carcinoma of lung. Said invention makes it possible to diagnosticate with a very high degree of confidence a non-small cell carcinoma of lung, including a squamous cell carcinoma, at a very early stage of the progression of a neoplastic aberration.
申请公布号 EA010571(B1) 申请公布日期 2008.10.30
申请号 EA20070001894 申请日期 2006.08.15
申请人 INSTITUT MOLEKULYARNOI GENETIKI ROSSIISKOI AKADEMII NAUK (IMG RAN) 发明人 MASHKOVA TAMARA, DMITRIEVNA;OPARINA NINA, YURIEVNA;ZINOVIEVA OLGA, LEONIDOVNA;KOPANTSEV EVGENY, PAVLOVICH;VINOGRADOVA TATYANA, VIKTOROVNA;ZINOVIEVNA MARINA, VALERIEVNA;ZBOROVSKAYA IRINA, BORISOVNA
分类号 C12Q1/68;C12N15/11 主分类号 C12Q1/68
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