发明名称 |
B-Blocker Pharmacogenetics in Heart Failure |
摘要 |
Polymorphisms in the beta-1 adrenergic receptor that (1) affect tolerability to beta-blocker treatment or (2) influence responsiveness to beta-blocker treatment are disclosed. Additionally, methods of predicting that an individual would obtain clinical improvement in left ventricular function as a result of beta-blocker therapy or identifying at least one individual that would obtain a clinical improvement in left ventricular function as a result of beta-blocker therapy are provided. Methods of treating patients characterized by such polymorphisms are also illustrated.
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申请公布号 |
US2008269346(A1) |
申请公布日期 |
2008.10.30 |
申请号 |
US20060816480 |
申请日期 |
2006.02.17 |
申请人 |
UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. |
发明人 |
JOHNSON JULIE;TERRA STEVEN |
分类号 |
A61K31/137;A61P9/00;C12Q1/68 |
主分类号 |
A61K31/137 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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