发明名称 |
PAPILLOMAVIRUS E2 POLYPEPTIDE USED FOR VACCINATION |
摘要 |
The present invention relates to the use of a nucleic acid molecule encoding at least one papillomavirus E2 polypeptide, or a vector, an infectious viral particle or a composition thereof for the preparation of a drug intended for treating a patient suffering from a persistent papillomavirus infection caused by at least one papillomavirus. The present invention also provides a vector comprising a nucleic acid molecule comprising a first nucleotide sequence encoding a papillomavirus E1 polypeptide and a second nucleotide sequence encoding a papillomavirus E2 polypeptide wherein the 3' portion of the first nucleotide which in the natural context is 100% identical to the 5' portion of the second nucleotide is modified so as to exhibit a percentage of identity between said portions of at most 75%. |
申请公布号 |
WO2008092854(A3) |
申请公布日期 |
2008.10.30 |
申请号 |
WO2008EP51032 |
申请日期 |
2008.01.29 |
申请人 |
TRANSGENE S.A.;BAUDIN, MARTINE;BALLOUL, JEAN-MARC;SILVESTRE, NATHALIE |
发明人 |
BAUDIN, MARTINE;BALLOUL, JEAN-MARC;SILVESTRE, NATHALIE |
分类号 |
C12N15/86;A61K39/12;C07K14/025;C12N7/04;C12N15/863 |
主分类号 |
C12N15/86 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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