发明名称 CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1.
摘要 <p>The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I), as well as methods of using the compounds and compositions to treat diabetes, hyperglycemia, obesity, hypertension, hyperlipidemia, metabolic syndrome, and other conditions associated with 11β-HSD type 1 activity.</p>
申请公布号 MX2008013484(A) 申请公布日期 2008.10.30
申请号 MX20080013484 申请日期 2007.04.05
申请人 ELI LILLY AND COMPANY. 发明人 NANCY JUNE SNYDER;ASHRAF SAEED;OWEN BRENDAN WALLACE;THOMAS DANIEL AICHER;THOMAS EDWARD MABRY;YANPING XU;PETER BIAGIO ANZEVENO;RENHUA LI;ALEXEI PAVLOVYCH KRASUTSKY;GREGORY ALAN STEPHENSON;HONGQI TIAN;LEONARD LARRY WINNEROSKI, JUNIOR
分类号 C07D403/04;A61K31/416;A61P3/10;A61P9/10 主分类号 C07D403/04
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