| 摘要 |
Compounds of the present invention find utility in the treatment of mamma lian cancers and especially human cancers including but not limited to malig nant, melanomas, glioblastomas, ovarian cancer, pancreatic cancer, prostate cancer, lung cancers, breast cancers, kidney cancers, cervical carcinomas, m etastasis of primary tumor sites, myeloproliferative diseases, leukemias, pa pillary thyroid carcinoma, non small cell lung cancer, mesothelioma, hypereo sinophilic syndrome, gastrointestinal stromal tumors, colonic cancers, ocula r diseases characterized by hyperproliferation leading to blindness includin g various retinopathies, rheumatoid arthritis, asthma, chronic obstructive p ulmonary disease, mastocytosis, mast cell leukemia, a disease caused by c-Ab l kinase, oncogenic forms thereof, aberrant fusion proteins thereof and poly morphs thereof, or a disease caused by c-Kit kinase, oncogenic forms thereof , aberrant fusion proteins thereof and polymorphs thereof.
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