发明名称 A NEW PROCESS FOR THE MANUFACTURING OF THE COMPOUND 2-HYDROXY-3-[5-(MORPHOLIN-4-YLMETHYL)PYRIDIN-2-YL]1H-INDOLE-5-CARBONITRILE 701
摘要 The present invention relates to a new process for the manufacture of the compound 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-carb onitrile as a free base and pharmaceutically acceptable salts thereof, parti cularly the 2-hydroxy-3-[5-(morpholin-4-ylmethyl)pyridin-2-yl]1H-indole-5-ca rbonitrile citrate, and to new intermediates prepared in said process suitab le for large scale manufacturing of said compound.
申请公布号 CA2684347(A1) 申请公布日期 2008.10.30
申请号 CA20082684347 申请日期 2008.04.17
申请人 ASTRAZENECA AB 发明人 THIERING, SWANTJE;RYBERG, PER;JANSSON, ANNETTE;HEDBERG, MARTIN;DELISSER, VERN;RADEVIK, ANDREAS
分类号 C07D401/04;A61K31/5355;C07D213/38 主分类号 C07D401/04
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