发明名称 NOVEL VIII FACTORS FOR THE TREATMENT OF TYPE A HEMOPHILIA
摘要 The present invention relates to improved variants of the human FVIII having at least one substitution in the A2 and/or C2 domain. The present invention also relates to their use 5 in the treatment of type A hemophilia, particularly in patients with inhibitors.
申请公布号 WO2008129180(A2) 申请公布日期 2008.10.30
申请号 WO2008FR50301 申请日期 2008.02.22
申请人 BIOMETHODES;HOSPICES CIVILS DE LYON;SABOULARD, DIDIER;PLANTIER, JEAN-LUC;DELCOURT, MARC;NEGRIER, CLAUDE;MENGUY, THIERRY;BLESA, STEPHANE;MARIN, SYLVIE 发明人 SABOULARD, DIDIER;PLANTIER, JEAN-LUC;DELCOURT, MARC;NEGRIER, CLAUDE;MENGUY, THIERRY;BLESA, STEPHANE;MARIN, SYLVIE
分类号 C07K14/43 主分类号 C07K14/43
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