ANTIBODY PRODUCING MICROORGANISM, ELEMENTS REQUIRED TO OBTAIN SAME, RESULTING ANTIBODIES, THERAPEUTIC COMPOSITIONS AND USE OF THEREOF

摘要

The invention relates to a microorganism that produces, secretes and injects single-domain recombinant antibodies into animal or plant eukaryote cells owing to the presence of a gene construction containing a type III secretion signal consisting of a sequence that codes for the first 20 amino acids at the amino-terminal end of protein EspF of Escherichia coli. In addition, said non-pathogenic or attenuated microorganisms can be used to prepare pharmaceutical compositions for the treatment of human or veterinary diseases.