发明名称 |
MODULATION OF ACTIVITY OF PRONEUROTROPHINS |
摘要 |
The present invention provides agents for inhibiting binding of a pro-neurotrophin to a Vps1 Op-domain receptor, in particular the binding of a pro-NGF or a pro-BDNF to a Sortilin receptor. The invention thus provides agents for the manufacture of a medicament, for treating and/or preventing disease or disorders such as but not limited to neurological, neuropsychiatric and ocular diseases, disorders, and degeneration as well as obesity, diabetes, pain and/or nociception in an individual. |
申请公布号 |
WO2008074329(A3) |
申请公布日期 |
2008.10.30 |
申请号 |
WO2007DK00567 |
申请日期 |
2007.12.21 |
申请人 |
NEURONICON APS;ANDERSEN, OLAV MICHAEL;NYKJAER, ANDERS |
发明人 |
ANDERSEN, OLAV MICHAEL;NYKJAER, ANDERS |
分类号 |
A61K38/17;A61K38/18;A61P25/00;C07K14/71;C07K16/28;G01N33/68 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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