发明名称 18-Membered macrocycles and analogs thereof
摘要 The present invention relates generally to the 18-membered macrocyclic antimicrobial agents called Tiacumicins, specifically, OPT-80 (which is composed almost entirely of the R-Tiacumicin B), pharmaceutical compositions comprising OPT-80, and methods using OPT-80. In particular, this compound is a potent drug for the treatment of bacterial infections, specifically C. difficile infections.
申请公布号 US2008269145(A1) 申请公布日期 2008.10.30
申请号 US20070882219 申请日期 2007.07.31
申请人 SHUE YOUE-KONG;HWANG CHAN-KOU;CHIU YU-HUNG;ROMERO ALEX;BABAKHANI FARAH;SEARS PAMELA;OKUMU FRANKLIN 发明人 SHUE YOUE-KONG;HWANG CHAN-KOU;CHIU YU-HUNG;ROMERO ALEX;BABAKHANI FARAH;SEARS PAMELA;OKUMU FRANKLIN
分类号 A61K31/7048;A61P31/04;C07H17/08 主分类号 A61K31/7048
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