EPOXY-CONTAINING POLY(ESTER AMIDES) AND METHODS OF USE
摘要
The invention provides aliphatic epoxy-containing PEA polymer compositions with film-forming properties. The aliphatic epoxy di-acids used in the invention PEA compositions include non-toxic fatty aliphatic epoxy homologs. A second, C-protected L-lysine-based monomer can be introduced into the polymer to provide additional chain flexibility. The invention PEA polymer compositions are useful for delivery of bioactive agents when administered internally or used in the manufacture of implantable medical devices. Biodegradable hydrogels can be made using the invention epoxy-containing PEAs.
申请公布号
WO2008021548(A3)
申请公布日期
2008.10.30
申请号
WO2007US18386
申请日期
2007.08.16
申请人
MEDIVAS, LLC;KATSARAVA, RAMAZ;TUGUSHI, DAVID;ZAVRADASHVILI, NINO;GOMURASHVILI, ZAZA, D.
发明人
KATSARAVA, RAMAZ;TUGUSHI, DAVID;ZAVRADASHVILI, NINO;GOMURASHVILI, ZAZA, D.