| 摘要 |
<p>The invention provides methods for treating diabetes and related disorders, such as metabolic syndromes (which includes insulin resistance), by administering an inhibitor of osteopontin (OPN), which includes an antibody, antibody fragment, siRNA, and aptamer. Also disclosed are methods for increasing glucose uptake by cells in a subject, by administering an inhibitor of OPN.</p> |
| 申请人 |
PFIZER INC.;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;BINGHAM, JUSTIN, THOMAS;CHAPMAN, JUSTIN, GUY;MORTH, MICHAEL, ALDAN;SYARS, DOROTHY |
发明人 |
BINGHAM, JUSTIN, THOMAS;CHAPMAN, JUSTIN, GUY;MORTH, MICHAEL, ALDAN;SYARS, DOROTHY |
