IMPROVED BACTERIAL TWO-HYBRID ASSAY

摘要

Disclosed is a method for rapidly and efficiently screening a substance (e.g., an antibody, a peptide) capable of interacting with a target substance. Specifically disclosed are: a novel bacterial two-hybrid assay utilizing the gene transfer by a phage; and a screening method comprising a combination of the bacterial two-hybrid assay with a phage display system. The bacterial two-hybrid assay and the screening method enable to rapidly and efficiently screen a substance (e.g., an antibody, a peptide) capable of interacting with a target substance.