发明名称 |
Novel Imaging Tracers for Early Detection and Treatment of Amyloid Plaques Caused by Alzheimer's Disease and Related Disorders |
摘要 |
The present invention relates to compounds and methods for imaging and treating Alzheimer's disease or an amyloidosis-associated pathological condition that utilize a novel amyloid imaging tracer for detecting amyloid deposits in a subject suffering from these conditions. In certain embodiments, the invention relates to [N-2[18F]fluoropropyl]-2-(4'-(methylamino)-phenyl)-6-hydroxybenzothiazole (F-18MHT) and dimers thereof.
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申请公布号 |
US2008267879(A1) |
申请公布日期 |
2008.10.30 |
申请号 |
US20080110686 |
申请日期 |
2008.04.28 |
申请人 |
THE GENERAL HOSPITAL CORPORATION |
发明人 |
ELMALEH DAVID R.;SHOUP TIMOTHY M.;FISCHMAN ALAN J. |
分类号 |
A61K31/428;A61K31/404;A61K31/4184;A61K31/423;A61K51/00;C07D209/04;C07D235/04;C07D263/54;C07D277/62;C07D417/12 |
主分类号 |
A61K31/428 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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