| 摘要 |
<p>A method of identifying a compound for use in therapy which modulates the interaction of S100A9 with a ligand comprising:
- determining whether a candidate compound is capable of modulating the interaction of S100A9 with RAGE or the interaction of S100A9 with a TLR (Toll like receptor), or
- determining whether a candidate compound is capable of binding to S 100A9 in a manner which disrupts binding of S100A9 with RAGE or the binding of S100A9 with a TLR,
to thereby identify whether the compound may be used in therapy.</p> |
