发明名称 2-Sulfinyl- and 2-sulfonyl-substituted imidazole derivatives and their use as cytokine inhibitors
摘要 The invention relates to 2-sulfinyl- or 2-sulfonyl-substituted imidazole derivatives of the formula (I) in which the radicals R1, R2, R3 and R4 have the meaning indicated in the description. The compounds of the invention have an immunomodulating and/or cytokine release-inhibiting effect and are therefore suitable for the treatment of disorders associated with an impairment of the immune system.
申请公布号 ZA200708203(B) 申请公布日期 2008.10.29
申请号 ZA20070008203 申请日期 2007.09.26
申请人 MERCKLE GMBH 发明人 ALBRECHT, WOLFGANG;STRIEGEL, HANS-GUENTR;TOLLMANN, KAROLA;MERCKLE, PHILIPP;LAUFER, STEFAN;GREIM, CORNELIA
分类号 A61K;A61P;C07D 主分类号 A61K
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