发明名称 COMPOUNDS FOR THE INHIBITION OF INTEGRINS AND USE THEREOF
摘要 The present invention is related to a compound of formula (I), wherein A is a nonaromatic heterocyclic ring., Ar is either absent or phenylene; 6 is a radical of formula (II), R2 is a hydrophobic moiety; and G is a radical containing one or more moieties selected from the group consisting of NH, OH and a basic moiety. The compounds are inhibitors of integrins, especially antagonists of the fibronectin receptor alpha5beta1, useful as anti-angiogenic agents.
申请公布号 KR20080095854(A) 申请公布日期 2008.10.29
申请号 KR20087017090 申请日期 2008.07.14
申请人 JERINI AG 发明人 ZISCHINSKY GUNTHER;STRAGIES ROLAND;OSTERKAMP FRANK;SCHARN DIRK;HUMMEL GERD;KALKHOF HOLGER;ZAHN GRIT;VOSSMEYER DORTE;CHRISTNER ALBRECHT CLAUDIA;REINEKE ULRICH
分类号 C07D401/12;A61K31/4545;A61P35/00;C07D471/04 主分类号 C07D401/12
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