<p>A method of reducing or inhibiting kinase activity of C KIT in a cell or a subject, and the use of such compounds for preventing or treating in a subject a cell proliferative disorder and/or disorders related to C KIT using a ompound of the present invention: Formula (I), or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof. The present invention is further directed to methods for treating conditions such as cancers and other cell proliferative disorders.</p>
申请公布号
MX2008013528(A)
申请公布日期
2008.10.29
申请号
MX20080013528
申请日期
2007.04.19
申请人
JANNSEN PHARMACEUTICA N.V.
发明人
FLORES, CHRISTOPHER;BALLENTINE, SHELLEY K.;WALL, MARK J.;ILLIG, CARL R.;RUDOLPH, M. JONATHAN;MOLLOY, CHRISTOPHER J.;MANTHEY, CARL L.;CHEN, JINSHENG;WILSON, KENNETH;MEEGALLA, SANATH K.;DESJARLAIS, RENEE L.