摘要 |
The present invention concerns the compounds of formula (I), the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein the dashed line designates an optional bond; R1 and R2 are each independently hydrogen, halogen, C1-6alkyl or C1-6alkyloxy; R3 and R4 are each independently hydrogen, C1- 6alkyl, phenyl or phenyl substituted with one, two or three substituents selected from halo, hydroxy, nitro, cyano, trifluoromethyl, C1- 6alkyl, C1-6alkyloxy, C1-6alkylthio, mercapto, amino, mono- and di(C1-6alkyl)-amino, carboxyl, C1-6alkyloxycarbonyl and C1-6alkylcarbonyl; Alk is C1-4alkanediyl; D is a pyrimidinone, piperidone or a benzimidozolidinone; having antipsychotic activity; their preparation, compositions containing them and their use as a medicine.
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