摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to novel compounds of general formula (I) , where R1 represents phenyl group, containing 1-3 substitutes, selected from halogen and cyano group; R2 represents pyridyl group, which has 1-3 substitutes, selected from monocyclic or polycyclic heterocyclic group, which can have 1-3 substitutes, selected from halogen atoms, cyanogroup, as well as other values of R2 radical, given in formula of invention, R3 represents phenyl group or pyridyl group, which has 1-2 substitutes, selected from halogen and trihalogenmethyl group; R4 represents hydrogen atom; and X represents -SO2-; its salt or its solvate. As well as to medication and pharmaceutical composition, inhibiting production or secretion of beta-amyloid protein, and containing compound of formula (I), and to application of compound of pt.1 in order to obtain medication. ^ EFFECT: obtaining novel compounds, inhibiting production or secretion of beta-amyloid protein. ^ 14 cl, 1 tbl, 296 ex |