| 发明名称 |
PTERIDINONE DERIVATIVES FOR USE AS STEAROYL COA DESATURASE INHIBITORS |
| 摘要 |
The present invention discloses pteridinone derivatives for use as inhibi tors of stearoyl-CoA desaturase having the structure of Formula (I) The comp ounds are useful in treating and/or preventing various human diseases, media ted by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
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| 申请公布号 |
CA2681560(A1) |
申请公布日期 |
2008.10.16 |
| 申请号 |
CA20072681560 |
申请日期 |
2007.10.05 |
| 申请人 |
CV THERAPEUTICS, INC. |
发明人 |
HENDERSON, IAN;LIN, TSUNG;PARKHILL, ERIC;CHISHOLM, JEFFREY;GLUSHKOV, AUDREY;KOLTUN, DMITRY;VASILEVICH, NATALYA;ZABLOCKI, JEFF;COLE, ANDREW;ZILBERSHTEIN, TIMUR |
| 分类号 |
A61K31/519;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/04;A61P9/10;A61P9/12;A61P35/00;A61P43/00;C07D475/00 |
主分类号 |
A61K31/519 |
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