摘要 |
<p>The invention relates to novel blockers for pharmaceutical compositions exhibiting antihistaminic activity and to a method for treating and preventing the development of different allergic diseases. The inventive blockers are in the form of substituted 2,3,4,5-tetrahydro-1h-pyrido[4,3-b]indoles of general formula (1) and the pharmaceutically acceptable salts and/or hydrates thereof, wherein R<SUP>1</SUP> is an aminogroup substituent selected from optionally substituted C<SUB>1</SUB>-C<SUB>5</SUB> alkyl, optionally substituted C<SUB>2</SUB>-C<SUB>4</SUB> alkenyl, optionally substituted C<SUB>1</SUB>-C<SUB>5</SUB> alkinyl, carbamoyl, thiocarbamoyl and a substituted mercapto group R<SUP>2</SUP> <SUB>i</SUB></p> |
申请人 |
ALLA CHEM, LLC;IVASHCHENKO, ANDREY ALEXANDROVICH;IVASHCHENKO, ALEXANDER VASILIEVICH;TKACHENKO, SERGEY YEVGENIEVICH;FROLOV, YEVGENIY BORISOVICH;MITKIN, OLEG DMITRIEVICH;KRAVCHENKO, DMITRI VLADIMIROVICH;OKUN, ILYA MATUSOVICH;SAVCHUK, NIKOLAY FILIPPOVICH |
发明人 |
IVASHCHENKO, ANDREY ALEXANDROVICH;IVASHCHENKO, ALEXANDER VASILIEVICH;TKACHENKO, SERGEY YEVGENIEVICH;FROLOV, YEVGENIY BORISOVICH;MITKIN, OLEG DMITRIEVICH;KRAVCHENKO, DMITRI VLADIMIROVICH;OKUN, ILYA MATUSOVICH;SAVCHUK, NIKOLAY FILIPPOVICH |