THERAPEUTIC AGENTS

摘要

The present invention is directed to therapeutic agents of the formula (I ) which are atypical antipsychotics and which arc useful in the treatment of neurological and psychiatric disorders associated with dopamine D2 and sero tonin 5-HT2A neurotransmission dysfunction. wherein; R1 is C1-6alkyl, which is unsubstituted or substituted with 1-6 fluoro, wherein R1 and the hydroxyl group on the ring are attached to the same carbon atom; or a pharmaceutical ly acceptable salt thereof.