摘要 |
A tubular tissue graft device is provided comprising a tubular tissue and a restrictive fiber matrix of a bioerodible polymer about a circumference of the tubular tissue. The matrix may be electrospun onto the tubular tissue. In one embodiment, the tubular tissue is from a vein, such as a saphenous vein, useful as an arterial graft, for example and without limitation, in a coronary artery bypass procedure. Also provided is method of preparing a tubular graft comprising depositing a fiber matrix of a bioerodible polymer about a perimeter of a tubular tissue to produce a tubular tissue graft device. A cardiac bypass method comprising bypassing a coronary artery with a tubular tissue graft device comprising a vein and a restrictive fiber matrix of a bioerodible polymer about a circumference of the vein also is provided. |
申请人 |
UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION;EL-KURDI, MOHAMMED;HONG, YI;SOLETTI, LORENZO;STANKUS, JOHN J.;VORP, DAVID A.;WAGNER, WILLIAM R. |
发明人 |
EL-KURDI, MOHAMMED;HONG, YI;SOLETTI, LORENZO;STANKUS, JOHN J.;VORP, DAVID A.;WAGNER, WILLIAM R. |