DELTA-8 DESATURASES AND THEIR USE IN MAKING POLYUNSATURATED FATTY ACIDS
摘要
The present invention relates to ?8 desaturase genes, which have the ability to convert eicosadienoic acid (EDA; 20:2 ?-6) to dihomo-?-linolenic acid (DGLA; 20:3 ?-6) and/or eicosatrienoic acid (ETrA; 20:3 ?-3) to eicosatetraenoic acid (ETA; (20:3 ?-3). Isolated nucleic acid fragments and recombinant DNA constructs comprising such fragments encoding ?8 desaturases along with a method of making long-chain polyunsaturated fatty acids (PUFAs) using these ?8 desaturases in oleaginous yeast are disclosed.
申请公布号
WO2008124194(A1)
申请公布日期
2008.10.16
申请号
WO2008US04700
申请日期
2008.04.10
申请人
E. I. DU PONT DE NEMOURS AND COMPANY;DAMUDE, HOWARD, GLENN;ZHU, QUINN, QUN