| 发明名称 |
3-HYDROQUINAZOLIN-4-ONE DERIVATIVES FOR USE AS STEAROYL CoA DESATURASE INHIBITORS |
| 摘要 |
The present invention discloses 3-hydroquinazolin-4-one derivatives for use as inhibitors of stearoyl-CoA desaturase. The compounds are useful in treating and/or preventing various human diseases, mediated by stearoyl-CoA desaturase (SCD) enzymes, especially diseases related to abnormal lipid levels, cancer, cardiovascular disease, diabetes, obesity, metabolic syndrome and the like.
|
| 申请公布号 |
US2008255161(A1) |
申请公布日期 |
2008.10.16 |
| 申请号 |
US20080100399 |
申请日期 |
2008.04.09 |
| 申请人 |
KOLTUN DMITRY;PARKHILL ERIC;BOZE MELANIE;ZABLOCKI JEFF;VASILEVICH NATALYA;MAYBORODA ELENA;GLUSHKOV ANDREI;COLE ANDREW;CHISHOLM JEFFREY |
发明人 |
KOLTUN DMITRY;PARKHILL ERIC;BOZE MELANIE;ZABLOCKI JEFF;VASILEVICH NATALYA;MAYBORODA ELENA;GLUSHKOV ANDREI;COLE ANDREW;CHISHOLM JEFFREY |
| 分类号 |
A61K31/519;A61K31/517;A61P9/10;C07D239/80;C07D471/04 |
主分类号 |
A61K31/519 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
