发明名称 |
DIPHENYL-DIHYDRO-IMIDAZOPYRIDINONES |
摘要 |
and the pharmaceutically acceptable salts and esters thereof X, R<SUB>1</SUB>, R<SUB>2</SUB>, Y<SUB>1 </SUB>and Y<SUB>2 </SUB>are described herein inhibit the interaction of MDM2 protein with a p53-like peptide and hence have anti proliferative activity.
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申请公布号 |
US2008255119(A1) |
申请公布日期 |
2008.10.16 |
申请号 |
US20080050235 |
申请日期 |
2008.03.18 |
申请人 |
DOMINIQUE ROMYR;GOODNOW ROBERT ALAN;QIAO QI;VU BINH THANH |
发明人 |
DOMINIQUE ROMYR;GOODNOW ROBERT ALAN;QIAO QI;VU BINH THANH |
分类号 |
A61K31/437;A61K31/5377;A61P35/00;C07D413/14;C07D471/04 |
主分类号 |
A61K31/437 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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