POLY(1,4-PIPERAZIN-2-ONES) AS ROD-LIKE PROTEIN- PROTEIN INTERACTION INHIBITORS AND THEIR PRODUCTION

摘要

The present invention generally relates to compositions including six membered heterocyclic 1, 4-diaza-2-one moieties covalently bonded by a hydrazine bond and processes for producing the same. The compositions of the present invention may be utilized as peptido- and/or proteomimetics, for example,' in connection with alpha-helical proteins, like Bcl-2 proteins.