TARGET PROTEIN AND TARGET GENE FOR DRUG DISCOVERY, AND SCREENING METHOD

摘要

Disclosed are: a target protein and a target gene for a physiologically active substance such as a medicinal agent; and a means for developing a novel physiologically active substance by using the target protein or the target gene. Specifically disclosed are: a target protein and a target gene for a physiologically active substance; a method for the screening of a substance capable of regulating a physiological activity; a physiological activity regulator; a method for producing a derivative of a physiologically active substance; a complex comprising a physiologically active substance and a target protein for the physiologically active substance, and a method for producing the complex; and a kit comprising a physiologically active substance or a salt thereof; a method for the determination of the occurrence or the risk of occurrence of a given disease or condition, a method for the determination of sensitivity to a physiologically active substance, and a kit for use in any one of the methods; and others.