发明名称 |
Agent improving proton-driven transporter-mediated absorption in digestive tract and process for producing the same |
摘要 |
The present invention provides a pharmaceutical preparation that can improve absorption of a pharmaceutical compound in the gastrointestinal tract and that provides, through oral administration or like method, a blood concentration from which sufficient remedial effects can be expected, and a method for producing such a preparation. The invention is directed to a pharmaceutical preparation exhibiting excellent gastrointestinal absorbability comprising a compound recognized by a proton-coupled transporter and a pH-sensitive polymer in an amount sufficient for the gastrointestinal tract to acquire a pH at which the proton-coupled transporter optimally absorbs the compound into a cell. <IMAGE> |
申请公布号 |
AU2004204541(B2) |
申请公布日期 |
2008.10.16 |
申请号 |
AU20040204541 |
申请日期 |
2004.01.08 |
申请人 |
OTSUKA PHARMACEUTICAL CO., LTD.;AKIRA TSUJI |
发明人 |
IKUMI TAMAI;AKIRA TSUJI;MASAAKI ODOMI;YOSHIMICHI SAI;HIDEKAZU TOYOBUKU |
分类号 |
A61K47/32;A61K45/08;A61P31/04;A61P31/12;A61P35/00;A61P43/00 |
主分类号 |
A61K47/32 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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