WATER STABILIZED AEROSOL FORMULATION SYSTEM AND METHOD OF MAKING

摘要

The invention relates to an aerosol formulation system comprising a primary package system and an aerosol formulation therein wherein the aerosol formulation comprises insulin, a propellant and an amount of water sufficient to reach equilibrium quantities based on the moisture sorption rate diffusing across the primary package system in which the formulation is contained. In addition, the invention relates to a process for preparing the aerosol formulation systems as described herein.