| 发明名称 |
QUINOLIN-4-ONE DERIVATIVES AS MODULATORS OF ABC TRANSPORTERS |
| 摘要 |
<p>The present invention relates to prodrugs of modulators of ABC transporters, particularly, CFTR modulators, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.</p> |
| 申请公布号 |
EP1979367(A2) |
申请公布日期 |
2008.10.15 |
| 申请号 |
EP20060848958 |
申请日期 |
2006.12.21 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
GROOTENHUIS, PETER D.J.;HADIDA RUAH, SARA;ZHOU, JINGLAN;HAZLEWOOD, ANNA;BINCH, HAYLEY |
| 分类号 |
C07F9/60;A61K31/47;A61K31/661;A61P29/00;A61P31/00;C07D215/56 |
主分类号 |
C07F9/60 |
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