发明名称 |
USE OF ACID SCAVENGERS FOR THE SYNTHESIS OF STANDARD LENGTH AND LONG-MER NUCLEIC ACID ARRAYS |
摘要 |
<p>Protective groups which may be cleaved with an activatable deprotecting reagent are employed to achieve a highly sensitive, high resolution, combinatorial synthesis of pattern arrays of diverse polymers. In preferred embodiments of the instant invention, the activatable deprotecting reagent is a photoacid generator and the protective groups are DMT for nucleic acids and tBOC for amino acids. This invention has a wide variety of applications and is particularly useful for the solid phase combinatorial synthesis of polymers.</p> |
申请公布号 |
EP1979088(A2) |
申请公布日期 |
2008.10.15 |
申请号 |
EP20060849218 |
申请日期 |
2006.12.28 |
申请人 |
AFFYMETRIX, INC. |
发明人 |
KUIMELIS, ROBERT, G.;MCGALL, GLENN, H.;GOLDBERG, MARTIN, J.;XU, GUANGYU |
分类号 |
B01J19/00;C07H21/00;C40B50/14 |
主分类号 |
B01J19/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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