发明名称 |
CARBONIC ANHYDRASE IX (G250) ANTIBODIES AND METHODS OF USE THEREOF |
摘要 |
The invention provides scFv antibodies and monoclonal antibodies that bind to and decrease an activity of Carbonic Anhydrase IX (G250). Also provided are methods of treating and/or preventing cancer, such as renal clear cell cancer. Also provided are methods of identifying a carbonic anhydrase IX (G250) protein. The invention additionally provides methods of modifying immune effector cells, and the immune effector cells modified thereby. |
申请公布号 |
EP1979379(A2) |
申请公布日期 |
2008.10.15 |
申请号 |
EP20060847501 |
申请日期 |
2006.12.04 |
申请人 |
DANA-FARBER CANCER INSTITUTE |
发明人 |
MARASCO, WAYNE, A.;LO, AGNES;XU, CHEN |
分类号 |
C07K16/30;A61K51/10;C07K16/40 |
主分类号 |
C07K16/30 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|