发明名称 DRUG CONJUGATES AND THEIR USE FOR TREATING CANCER, AN AUTOIMMUNE DISEASE OR AN INFECTIOUS DISEASE
摘要 Drug-Linker-Ligand Conjugates are disclosed in which a Drug is linked to a Ligand via a peptide-based Linker unit. In one embodiment, the Ligand is an Antibody. Drug-Linker compounds and Drug compounds are also disclosed. Methods for treating cancer, an autoimmune disease or an infectious disease using the compounds and compositions of the invention are also disclosed.
申请公布号 EP1545613(A4) 申请公布日期 2008.10.15
申请号 EP20030772186 申请日期 2003.07.31
申请人 SEATTLE GENETICS, INC. 发明人 SENTER, PETER, D.;DORONINA, SVETLANA;TOKI, BRIAN, E.
分类号 A61K39/395;A61K47/48;A61P35/00;C07K5/02;C07K5/06;C07K16/12;C07K16/30;C07K16/46;C12P21/08 主分类号 A61K39/395
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