| 发明名称 |
N-CYCLOPENTYL MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY |
| 摘要 |
<p>The present invention is directed to compounds of formula (I) (wherein R1, R3, R4, R5, R6, R7, R8, X, n, x and y are defined herein) which are use-ful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-5 and/or CCR-3.</p> |
| 申请公布号 |
CA2382880(C) |
申请公布日期 |
2008.10.14 |
| 申请号 |
CA20002382880 |
申请日期 |
2000.06.08 |
| 申请人 |
MERCK & CO., INC. |
发明人 |
FINKE, PAUL E.;MACCOSS, MALCOLM;MILLS, SANDER G.;SHAH, SHRENIK K.;OATES, BRYAN;CHAPMAN, KEVIN T.;SHEN, DONG-MING;KIM, DOOSEOP;HILFIKER, KERRY A.;GUTHIKONDA, RAVI N.;LOEBACH, JENNIFER L. |
| 分类号 |
C07D401/04;C07D487/04;A61K31/437;A61K31/4439;A61K31/445;A61K31/4468;A61K31/4525;A61K31/454;A61K31/4545;A61K31/4709;A61K31/506;A61P9/10;A61P11/02;A61P11/06;A61P17/00;A61P19/02;A61P27/02;A61P29/00;A61P31/00;A61P31/18;A61P37/00;A61P37/02;A61P37/08;A61P43/00;C07D211/14;C07D211/18;C07D211/20;C07D211/24;C07D211/30;C07D211/34;C07D211/58;C07D277/30;C07D401/06;C07D401/12;C07D401/14;C07D405/14;C07D413/04;C07D413/06;C07D413/10;C07D417/04;C07D471/04 |
主分类号 |
C07D401/04 |
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