发明名称 Methods for producing ex vivo models for inflammatory disease and uses thereof
摘要 The invention relates to methods for inducing a pro-asthma/pro-inflammatory like state in a resident tissue cell, comprising contacting the cell with one or more cytokines, e.g., IL-beta, TNFalpha or both. Methods are also disclosed for identifying genes that regulate responses to anti-inflammatory drugs, to methods for drug screening, and to methods for identifying genes that correlate with various pro-asthma/pro-inflammatory disease phenotypes.
申请公布号 US7435548(B2) 申请公布日期 2008.10.14
申请号 US20070879066 申请日期 2007.07.16
申请人 DECODE GENETICS EHF.;THE CHILDREN'S HOSPITAL OF PHILADELPHIA 发明人 HAKONARSON HAKON;GRUNSTEIN MICHAEL M.
分类号 C12Q1/68;G01N33/53;G01N33/564 主分类号 C12Q1/68
代理机构 代理人
主权项
地址