PROTEASE PRODUCT OF REDUCED ALLERGENICITY

摘要

A novel protease product suitable for admixture to washing compositions and exhibiting substantially attenuated allergenic properties is prepared by cultivating strains of Bacillus licheniformis which have been mutated to block their synthesis of proteases other than Subtilopeptidase A (subtilisin). The commercial Bacillus licheniformis derived protease products are mixtures of subtilisin and a non-serine protease of lower stability and greater allergenicity than subtilisin.