发明名称 |
Process for delivery of polynucleotides to the prostate |
摘要 |
Disclosed is a system for providing in vivo delivery of polynucleotides to mammalian prostate cells using an intravascular administration route. The polynucleotides are inserted in an injection solution into a mammalian vasculature. Insertion of the injection solution at an appropriate rate increases the volume of extravascular fluid in the tissue thereby facilitating delivery of the polynucleotide to the cell.
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申请公布号 |
US7435723(B2) |
申请公布日期 |
2008.10.14 |
申请号 |
US20030680742 |
申请日期 |
2003.10.06 |
申请人 |
MIRUS BIO CORPORATION |
发明人 |
HAGSTROM JAMES E.;NOBLE MARK;HEGGE JULIA;BUDKER VLADIMIR G. |
分类号 |
A61K48/00;A01N63/00;A61K47/48;C07H21/00;C12N15/87 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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